Tutorial Workshop on Parameter Estimation for Biological Models

Talks: SAS Hall 1102; Coffee Breaks: SAS Hall 4104

Thursday July 28th. Theme: Least Squares Estimation
8:00 – 9:00 Registration SAS Hall 4104
9:00 – 9:15 Welcome to the workshop (M.S. Olufsen / A.L. Lloyd)
9:15 – 10:45 Tutorial lecture: Introduction to parameter estimation in a least squares framework (Kevin Flores) PDF of slides and slides on sensitivities ; Video of talk
10:45 – 11:15 Coffee break
11:15 – 12:00 Research talk: A mathematical methodology for determining information content in demographic data for ecotoxicology studies (H.T. Banks) PDF of slides (Apologies: no video)
12:00 – 1:30 Lunch break
1:30 – 2:15 Research talk: Parameter estimation in cardiovascular dynamics modeling (Mette S. Olufsen) PDF of slides ; Video of talk
2:30 – 4:30 Computer Practical: Sensitivity Analysis and Least Squares Parameter Estimation for an Epidemic Model (Alun L. Lloyd) Code and other materials
5:00 – 7:00 Poster session (light refreshments provided)
 
Friday July 29th. Themes: Identifiability and Forward Propagation of Uncertainty
9:00 – 10:30 Tutorial lecture: Identifiability (Marisa Eisenberg) PDF of slides ; Video of talk
10:30 – 11:00 Coffee break
11:00 – 12:30 Computer practical on identifiability (Marisa Eisenberg and Chris Durden)
Materials for practical
12:30 – 2:00 Lunch break
2:00 – 3:30 Tutorial lecture: Uncertainty quantification for biological models (Ralph Smith)
PDF of slides ; Video of talk
3:30 – 5:00 Computer practical: Numerical techniques for active subspaces, surrogate model construction and uncertainty propagation (Ralph Smith)
Slides and code for practical
5:00 – 5:30 Coffee break
5.30 – 6.30 Keynote talk: Connecting models with data: identifiability and parameter estimation of multiple transmission pathways (Marisa Eisenberg) Video of talk
 
Saturday July 30th. Themes: Bayesian Approaches and Filtering Methods
9:00 – 10:30 Tutorial lecture: Inverse problems in the Bayesian framework (Daniela Calvetti) PDF of slides ; Video of talk
10:30 – 11:00 Coffee break
11:00 – 12:30 Computer practical on nonsequential Bayesian (A. Arnold/ F. Hamilton)
PDF of slides and zip fie of codes
12:30 – 2:00 Lunch break
2:00 – 3:00 Keynote talk: Compensating for lack of data with expert knowledge: how hierarchical models can be used to solve the very underdetermined MEG inverse problem (Daniela Calvetti) (Apologies: no video)
3:00 – 4:00 Tutorial lecture: Bayesian filtering (Franz Hamilton & Andrea Arnold)
PDF of slides (Apologies: no video)
4:00 – 4:30 Coffee break
4:30 – 5:30 Computer practical: Kalman filtering in a mass-spring system (Arnold/Hamilton)
PDF of slides
 
Dinner: outing to downtown Raleigh. Local participants will drive.
 
Sunday July 31st. Theme: Mixed Effects Models
9:00 – 10:30 Tutorial talk: Introduction to mixed-effects modeling (H. Tran) PDF of slides ; Video of talk: part 1 and part 2
10:30 – 11:00 Coffee break
11:00 – 12:00 Keynote talk: Mixed-effects biological models: estimation and inference (Hulin Wu) PDF of slides ; Video of talk
12:00 End of workshop

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